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[ccp4bb] PhD position in Germany

Dear all,
Please find below the advertisement for a PhD position in our research group:
PhD position in Structural Biology at JGU/IMB Mainz, Germany

A PhD position is available in the group of Eva Wolf at the Johannes Gutenberg University

(JGU) and the Institute of Molecular Biology (IMB) in Mainz, Germany. Research in the Wolf

group is focused on the structural, biochemical and biophysical analysis of proteins involved

in circadian (day-time dependent) regulation (e.g. Czarna et al, Cell 2013; Schmalen et al,

Cell 2014) and in genome maintenance (e.g. Witosch et al, NAR 2014).

To elucidate the molecular mechanisms underlying circadian gene regulation and circadian

physiology, the PhD student will apply a wide range of techniques including 3D-structural

analyses (e.g. X-ray crystallography, Cryo-EM, SAXS, Crosslink-MS), biochemical and

biophysical protein interaction studies as well as UV/VIS spectroscopy. To produce highly

pure proteins and protein complexes for these applications, she/he will perform cloning,

recombinant protein _expression_ (E.coli, insect cells) and protein purification using FPLC

systems. Within collaborations, she/he will also analyze clock protein interactions and protein

functions in cell-based approaches and in in vivo systems. Candidates with a strong interest

in structural biology and protein biochemistry combined with a significant previous exposure

to these research areas during their master education are encouraged to apply.

The prospective PhD student will be affiliated with IMB’s International PhD program (IPP)

and must have a good command of English. PhD candidates must officially apply via the

International PhD Programme (IPP, www.imb-mainz.de/students-postdocs/international-phd-programme). The deadline for registration at the IPP is May 26th 2020. Informal inquiries should be addressed

to Eva Wolf (evawolf1@uni-mainz.de).

With best regards,
Eva Wolf

Prof. Dr. Eva Wolf

Structural Chronobiology
IMB and University Mainz Ackermannweg 4 55128 Mainz, Germany



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