[ccp4bb] postdoc positon at Aarhus University, receptor-antibody complexes

[Gregers Rom Andersen <gra@MBG.AU.DK>]

We are seeking applicants for a postdoc position in structural biology to join the research team of Professor Gregers Rom Andersen at the Department of Molecular Biology and Genetics for pursuing structure determination of a receptor-ligand complex. The position is for a starting period of 2 years and is available from 1st September 2020 or as soon as possible hereafter.

The project concerns structural studies of immunoglobulin E (IgE ) and its receptors to clarify how antibody binding to receptors elicits immune responses. The structural targets are complexes of recombinant IgE antibodies and recombinant IgE receptors. Nanobody development may be used for target modulation and stabilization. Structure determination will take advantage of single particle cryo-EM. Grid screening and data collection will take place at local Titan Krios microscopes and international facilities like eBIC. An excellent computational infrastructure for single particle EM data processing is available through a common computational cluster.

Applicants should hold a PhD in molecuar biology, biochemistry, nanotechnology, biomedicine or related field. Candidates with experience in membrane protein purification and single particle EM will be preferred, but prior experience with other structural biology techniques is also considered positive.

More information is available at 

https://www.au.dk/om/stillinger/job/postdoc-position-in-structural-biology/

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