Two postdoctoral positions are available in the Valiyaveetil group at Oregon Health and Science University in Portland, Oregon. The Valiyaveetil group investigates structure and function of ion channels and transporters using a combination of unnatural amino acid mutagenesis, electrophysiology, structural biology and spectroscopy. See references [Nat Commun, (2019), 9, 5055; PNAS ( for examples of recent research from the lab. The group is a part of the Program in Chemical Biology in the Department of Chemical Physiology and Biochemistry.
The positions are suitable for highly motivated candidates with a recent (less than 1 year) Ph.D. in Biochemistry, Biophysics or a related discipline. The first candidate will investigate ion channels using unnatural amino acid mutagenesis, functional and structural studies. Candidates for this position should have prior research experience in ion channels and have expertise in carrying out electrophysiological measurements using two-electrode voltage clamp or patch clamp. The second candidate will investigate transporters using a combination of biochemical, spectroscopic and structural approaches. Candidates for this position should have prior experience in membrane protein biochemistry and prior expertise in structural approaches such as crystallography or cryo-EM or in fluorescence or EPR spectroscopy will be a plus. These positions provides the candidates with a unique opportunity to enhance their skill set with the techniques for membrane protein engineering using unnatural amino acid mutagenesis.
The Valiyaveetil lab is well equipped to carry out structural and functional studies of ion channels and transporters. OHSU provides an excellent scientific environment. Portland is consistently rated as one of the most livable cities in the US.
To apply send CV, a 1-2 page description of graduate research and future research plans along with contact information for three references by email to: valiyave@ohsu.edu
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