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[ccp4bb] Postdoctoral Position at Exeter University

A postdoctoral position is available on a multidisciplinary project between the group of Prof Littlechild at the Henry Wellcome Building for Biocatalysis and Prof Frank Volmer in Physics within the new LSI Building in association with the Physics Department. The aim is  to study enzyme structure, stability and mechanism, and enzyme folding with state-of the art methodologies including single-molecule optical nanosensors, X-rays, and molecular dynamics simulations. This project will be part of the UKRI Molecular Mechanics Initiative at the University of Exeter which is a cutting-edge research programme that aims to achieve breakthroughs in how to detect, analyse, and manipulate molecules at the ultimate single-molecule level.

Experience with gene cloning and over-_expression_, enzyme purification, X-ray structural analysis, mutational analysis and application of other biophysical techniques is required. Familiarity with surface immobilisation of proteins and enzymes, molecular dynamics simulations, Raman and SERS protein analysis, and electrochemical sensors is desirable.

The successful candidate can be appointed as Postdoctoral Research Fellow (Grade F) depending on the skills and experience the individual can bring to the role.

Postdoctoral Research Fellow on Grade F from £35,211 up to £39,609 per annum. Please find further job specifications on the Exeter web site and any interested candidates should apply by the closing date of 28th May. For further information, please contact Prof J Littlechild, email J.A.Littlechild@exeter.ac.uk, or telephone (01392) 7223468. 





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