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[ccp4bb] Post-doctoral research position available

Job Description – Postdoctoral fellow

A postdoctoral position in structural biology is available as of June 1st, 2019 in the laboratory of Dr. Aishwarya Prakash at the Mitchell Cancer Institute (MCI) part of the University of South Alabama in Mobile, AL, USA.

We are seeking a highly motivated individual to join a motivated, productive, and hardworking research team. The candidate will carry forth two or three research projects and be a part of a close-knit, collaborative environment at the Mitchell Cancer Institute.

The laboratory is interested in studying complexes involved in the repair of mitochondrial DNA via the base excision repair pathway (BER). More specifically, the lab is involved in studying the role of DNA glycosylases in the repair of the mitochondrial genome. The laboratory uses a combination of cellular, biochemical, and biophysical approaches to study the complexes formed during BER.  Some of these techniques include in vitro binding, activity, and repair assays, multi-angle light scattering, X-ray crystallography, and SAXS. The laboratory is equipped with a state-of the art X-ray diffraction unit and other shared resources available at MCI. More recently the laboratory has been involved with studying the role of DNA glycosylases in cells using CRISPR gene editing and microscopy approaches.

Specific qualifications include:

-       Ph.D. degree in structural biology, biochemistry, or cancer biology

-       Experience with cloning, protein _expression_, purification, and protein crystallization are a plus

-       Experience in basic tissue culture techniques is essential

-       Preference will be given to candidates with an understanding of gene knock out strategies

-       Verbal and written communication skills in English is necessary

-       Good laboratory documentation practices are a must

Applications will be reviewed until the position is filled. Interested applicants should send a curriculum vitae, and three letters of reference to mciapjobs@gmail.com.

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