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[ccp4bb] Sr.Scientist position at Cedars-Sinai Hospital, Los Angeles



Dear CCP4 community,
 
We (Murali Laboratory at Cedars-Sinai Medical Center, Los Angeles) are seeking an experienced Structure Biologist/X-ray crystallographer. The position is at the Senior Scientist (Project Scientist) level and will be filled as soon as possible.
 
The laboratory operates focusing on a number of immune and oncology-associated protein targets.  We are equipped with a wide variety of instruments including a Rigaku MicroMax 007-HF X-ray generator/RAXIS IV++ detector, a SensiQ Pioneer SPR system and Art Robbins Gryphon and Scorpion robotics.  More details about the laboratory can be found at: http://cedars-sinai.edu/Research/Research-Labs/Murali-Lab/index.aspx
 
Suitable candidates would possess two or more of the following skills:
1) Extensive experience in bacterial and/or insect cell expression/purification
2) Extensive experience with FPLC and HPLC for protein purification/characterization
 	3) Extensive experience with standard molecular biology techniques, including LIC, qRT-PCR and SDM
 	4) Some experience using SPR and/or ITC for analyzing both protein-protein and protein-small molecule interactions
5) At least 2-3 years of post-doctoral experience in protein crystallization and structure determination and experience in synchrotron-based structure biology experiments.
7) Experience in Thermal shift assay, ELISAs, protein-DNA complex preparation and some experience in drug development including Fragment based approaches are highly desirable. 

To apply, please use the following web page:
 
https://jobs.cedars-sinai.edu/job/los-angeles/project-scientist-biologist-biochemist-x-ray-crystallography-murali-lab/252/11419290

Regards,
Ram

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