[ccp4bb] Postdoc position in gene regulation, Bernecky group (IST Austria)

[Carrie Bernecky <carrie.bernecky@IST.AC.AT>]

    We are inviting applications for one postdoctoral position at the
    Institute of Science and Technology (IST) Austria to study the
    structure and function of intellectual-disability associated
    proteins and their involvement in chromatin modification.
    
    The project is a collaboration between two groups at IST: the
    Bernecky group, which studies the structural basis of
    transcriptional and post-transcriptional gene regulation, and the
    Novarino group, which focuses on the genetic and molecular basis of
    neurodevelopmental disorders. The goal of the joint project will be
    to elucidate molecular mechanisms responsible for the development of
    autism and intellectual disability. The successful candidate will
    use biochemical, structural, and genomic techniques to investigate a
    frequently mutated protein and how it may link transcription and
    chromatin modification.
    
    We are looking for a highly motivated scientist holding a Ph.D. in
    structural biology or biochemistry. Candidates should have
    experience in recombinant protein _expression_ and purification of
    multi-subunit protein complexes. Experience in chromatin biology,
    nucleosome reconstitution, and/or cryo-electron microscopy is a
    plus.
    
    Our facilities include several transmission electron microscopes
    (TEMs) for negative stain and cryo-EM sample screening, including a
    FEI Tecnai 12 (120 kV) equipped with a CCD camera and a Thermo
    Fisher Glacios cryo-TEM (200 kV) equipped with a Falcon III direct
    electron detector. A 300-kV Thermo Fisher Titan Krios TEM equipped
    with state-of-the-art direct electron detectors (Falcon III, K3) is
    available for high-resolution data collection.
    
    If you are interested, please send a cover letter CV, and references
    to Carrie Bernecky (carrie.bernecky@ist.ac.at).
    
    Best wishes,
    Carrie
    
    
    Links:
    Biochemistry @ IST: https://biochemistry.ist.ac.at/
    Cryo-EM @ IST: http://cryo-em.ist.ac.at/
    Facilities @ IST:
    https://ist.ac.at/en/research/scientific-service-units/
    Bernecky group: https://ist.ac.at/en/research/bernecky-group/
    Novarino group: https://ist.ac.at/en/research/novarino-group/
    
-- 
Carrie Bernecky
Institute of Science and Technology Austria
Am Campus 1
3400 Klosterneuburg
Austria

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