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[ccp4bb] Postdoc position in Heidelberg, Germany
WANTED: 2 experienced Postdocs
This project will explore Nanobody binding to the human norovirus capsid protein using a combination of X-ray crystallography and cryo-EM. These Nanobodies are expected to work as potential antivirals and could lead into clinical trials if successful. A massive library of Nanobodies are ready to be tested ;)
See: https://www.dkfz.de/en/noroviren/index.php
Previous studies:
*Nanobodies targeting norovirus capsid reveal functional epitopes and potential mechanisms of neutralization.
PLoS Pathog. 2017 Nov 2;13(11):e1006636.
*Nanobody binding to a conserved epitope promotes norovirus particle disassembly.
J Virol. 2015 Mar;89(5):2718-30.
Our lab is fully equipped to carryout all experiments and we have plenty of beamline access.
Furthermore, a collaboration (including travel and research stays) with an Australian partner is also possible (Gold Coast/ Queensland).
Two qualified Postdocs with experience in solving and refining X-ray structures are urgently needed.
Email: g.hansman@dkfz.de
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