[ccp4bb] Electron microscopy support position @ CSSB, Hamburg

[Thomas White <thomas.white@DESY.DE>]

Hi everyone,

The CryoEM facility at CSSB in Hamburg is growing
(https://www.cssb-hamburg.de/facilities/cryo_em/index_eng.html)

We are currently looking for an EM support scientist to complement our
Team.  A job description is pasted below - however, we are totally
aware, that everyone contributes her/his own expertise, and that this
may change some of the responsibilities described.

For more information, or any other questions, please contact:
Carolin Seuring <carolin.seuring@cssb-hamburg.de>


Electron Microscopy Support (m/f/D) - Salary Level 13 TV-L -

The position commences as soon as possible and is permanent. This
position is also suitable for part time employment.

The Centre for Structural Systems Biology (CSSB) was created with the
mission to use cutting edge technologies and methods to investigate how
pathogens infect humans. Part of this mission are the CSSB Core
Facilities that provide access to technology and research services for
bio-sciences. Alongside these facilities, the multi-user facility for
electron cryo-microscopy (cryoEM) has started its operation in 2017,
and is positioned on the Science Campus Bahrenfeld, being also home to
the Deutsches Elektronen-Synchrotron DESY. Our facility is currently
the most advanced centre for cryoEM in the north of Germany housing
five electron microscopes: two Titan Krios instruments equipped with
phase plates, energy filters, K3 and Falcon 3 direct detectors, a Talos
Arctica with a phase plate and a Falcon 3 direct detector, a Talos
L120C and an Aquilos FIB cryo-SEM for preparing lamellae of thick
samples, such as vitrified cells or crystals. Auxiliary equipment and
nearby lab space for sample preparation and cell culture work complete
the workflows. We primarily focus on single particle analysis and
electron cryo-tomography. The facility is set up to handle biological
samples up to German biosafety level 2. 

Nature of the job

85% equipment set-up and operation, equipment maintenance, 15%
user-training & assistance:

Responsible for the day-to-day running and maintenance of the electron
microscopes and associated sample preparation equipment

Manage and operate the cryoEM instruments and associated equipment,
this includes first-fault diagnosis, and maintenance work

Assist in improving set-ups for the different cryoEM modalities (SPA,
Tomo) and the implementation of additional workflows (correlative
microscopy, microED)

Work with our computing scientist to ensure a seamless interface
between data collection and data processing

Establish and implement schedules for microscope hardware and software
maintenance, and support alignments and performance checks, to ensure
that the facility is operating at peak performance

Coordinate repairs with microscope supplier’s service engineers

Work with in house engineers and other facilities provide instructions,
assistance and consultation to faculty, students, staff members
regarding the TEM equipment and optimal processes

Perform other related duties incidental to the work described above

Your Profile

Experience in cryoEM (hardware and/or software), X-ray
technology, imaging detectors, or computational work at the interface
hardware/software

Experience in cryoEM & understanding the basics of
electron optics and vacuum systems

Previous experience in microscope control and acquisition software
packages for single particle analysis or tomography or one of the
following programming interfaces/languages: Python, C++, Java, LabView,
SerialEM

Good English language skills (both written and oral)

Experience with managing, analyzing, and improving complex workflows

Demonstrated record keeping and organization skills

Ability to proactively plan maintenance work and increase microscope
uptime & performance

Attention to detail

A desire to learn, and a willingness to share knowledge

Self-driven and organized

Your responsibilities within the team can be adjusted to best fit your
specific skill-set.

For more information please visit:
https://www.uni-hamburg.de/uhh/stellenangebote/technisches-bibliotheks-und-verwaltungspersonal/technik-und-service-und-sonstiges/17-02-20-tvp-602-1-en.pdf

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