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[ccp4bb] Phenix Postdoc Position - Berkeley, California

Postdoctoral Researcher
Lawrence Berkeley Laboratory
Job ID: 89267
Division: Molecular Biophysics & Integrated Bioimaging (Computational Crystallography Initiative)
Date Opened: 12/23/2019

Summary:  Berkeley Lab’s Molecular Biophysics and Integrated Bioimaging Division has an opening for a Postdoctoral Researcher. In this role you will develop new computational methods for the structure determination and refinement of protein structures using the PHENIX software system. Primary duties and responsibilities will include development and implementation of numerical methods and new computational protocols, including the application of machine learning methods. The Phenix software is used worldwide for the determination of atomic structures using X-ray and neutron crystallography and cryo-electron microscopy. The software is developed as part of an international collaboration supported by the National Institutes of Health and the Phenix Industrial Consortium.

To apply visit - https://lbl.taleo.net/careersection/2/jobdetail.ftl?job=89267


• Development and implementation of computational algorithms for structure determination using crystallography and cryo-electron microscopy including: improved methods for the optimization of models and automated detection of model heterogeneity.
• Application of machine learning methods to problems in crystallography and cryo-electron microscopy.
• Develop and test new components of the PHENIX software system in collaboration with others
• Document software developments.
• Collaborate with other researchers in the PHENIX program.
• Interact with P.I.s, other postdocs, scientists and external collaborators involved in the PHENIX project.
• Publication of research results in scientific journals and presentation of results at scientific meetings.

Additional Responsibilities as needed:

• Participate in workshop and tutorials to educate researchers in the use of Phenix
• Actively participate in writing progress reports

What is Required: 

• Ph.D. in computational crystallography, computational cryo-electron microscopy, computational biology, bioinformatics, computational chemistry or a related field
• Demonstrated experience in developing computational algorithms for solving problems
• Demonstrated experience with computational methods development
• Publications in macromolecular crystallography, cryo-electron microscopy or closely related fields
• Familiarity with Python, C++ and other software development tools
• Good programming and mathematical skills
• Strong interpersonal skills and the ability to work in a team environment 

Additional Desired Qualifications:

• Familiarity with macromolecular structure or computational chemistry.
• Experience with the practical aspects of crystallography and/or cryo-electron microscopy.

The posting shall remain open until the position is filled.


• This is a full time, 2 year postdoctoral appointment with the possibility of renewal based upon satisfactory job performance, continuing availability of funds and ongoing operational needs. You must have less than 3 years paid postdoctoral experience. Salary for Postdoctoral positions depends on years of experience post-degree.	
• Full-time, M-F, exempt (monthly paid) from overtime pay.
• This position is represented by a union for collective bargaining purposes.
• Salary will be predetermined based on postdoctoral step rates.
• This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
• Work will be primarily performed at: Lawrence Berkeley National Lab, 1 Cyclotron Road, Berkeley, CA.

Learn About Berkeley Lab:

Berkeley Lab (LBNL) addresses the world’s most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab’s scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy’s Office of Science.

Working at Berkeley Lab has many rewards including a competitive compensation program, excellent health and welfare programs, a retirement program that is second to none, and outstanding development opportunities.  To view information about the many rewards that are offered at Berkeley Lab- Click Here.

Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4.  Click here to view the poster and supplement: "Equal Employment Opportunity is the Law.

Paul Adams
Division Director, Molecular Biophysics & Integrated Bioimaging, LBL (http://biosciences.lbl.gov/divisions/mbib)
Principal Investigator, Computational Crystallography Initiative, LBL (http://cci.lbl.gov)
Vice President for Technology, the Joint BioEnergy Institute (http://www.jbei.org)
Principal Investigator, ALS-ENABLE, Advanced Light Source (http://als-enable.lbl.gov)
Division Deputy for Biosciences, Advanced Light Source (https://als.lbl.gov)
Laboratory Research Manager, ENIGMA Science Focus Area (http://enigma.lbl.gov)
Adjunct Professor, Department of Bioengineering, U.C. Berkeley (http://bioeng.berkeley.edu)
Adjunct Professor, Comparative Biochemistry, U.C. Berkeley (http://compbiochem.berkeley.edu)

Building 33, Room 347
Building 978, Room 4126
Building 977, Room 180C
Tel: 1-510-486-4225

Lawrence Berkeley Laboratory
1 Cyclotron Road
BLDG 33R0345
Berkeley, CA 94720, USA.

Executive Assistant: Ashley Dawn [ ashleydawn@lbl.gov ][ 1-510-486-5455 ]


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