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A postdoc position
is available in the team of Valerie Lamour in the Department of Integrated Structural Biology,
at the Institute of Genetics and Molecular and Cellular Biology-IGBMC, Strasbourg, France. DNA topoisomerases are large molecular machines involved in the regulation of DNA topology during cellular processes like DNA replication, transcription and chromosome segregation.
Our team works on the function of DNA topoisomerases nucleoprotein complexes with an integrated structural biology approach combining x-ray crystallography and high-resolution cryoEM with biochemical analysis*. The IGBMC is one of the leading biomedical research institutions located at the heart of Europe. The Integrated structural Biology department is coordinating center of the
national infrastructure FRISBI (frisbi.eu) and one of the French center for the european infrastructure INSTRUCT-ERIC (structuralbiology.eu), that provide access to cutting-edge facilities in structural biology, including cryo-EM with a Titan Krios electron
microscope.
Applicants should have experience in structural biology as well as protein _expression_ and purification. First hands-on experience in cryo-electron microscopy would be considered a strong advantage. The position is starting
between June and September 2020 and is funded for initially 2 years with the possibility of extension. Applications including a cover letter outlining research interests, CV, list of publications, and names of 2-3 references should be sent via e-mail to
lamourv@igbmc.fr For more information :
http://www.igbmc.fr/lamour Valérie Lamour, Associate Professor IGBMC Team leader "Chromatin stability and DNA mobility"
lamourv@igbmc.fr
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http://igbmc.fr/lamour *Related references: https://doi.org/10.1038/s41467-019-12914-y https://doi.org/10.1021/acs.jmedchem.8b01928 https://doi.org/10.1038/s41598-018-27606-8 https://doi.org/10.1093/nar/gkt560
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