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[ccp4bb] PostDoc position at EMBL Grenoble to work on ESRF beamline MASSIF-1 - closing date 15/12/19

Dear All,

One more week to apply for this exciting position! - closing date 15/12/19

we have a post-Doc position available here at EMBL Grenoble shared between the high throughput crystallisation team (https://www.embl.fr/services/ht_crystallisation/index.html) and the synchrotron team (https://www.embl.fr/research/unit/mccarthy/index.html) to work with me on ESRF beamline MASSIF-1 (http://www.esrf.eu/MASSIF1). MASSIF-1 has pioneered fully automated data collection, including sample location and decision making algorithms (see https://doi.org/10.1107/S2059798318003728 http://dx.doi.org/10.1107/S1399004715011918 http://dx.doi.org/10.1107/S1600577515016604) Next year will see two exciting upgrades to the beamline - first, the ESRF will be coming back on-line after completely re-building the accelerator (https://www.esrf.eu/about/upgrade) as the worlds first fourth generation high energy synchrotron - ESRF-EBS - we will be upgrading the beamline optics to maximise the capabilities of the new source. Second, the experimental station of MASSIF-1 will be completely refurbished to have a new diffractometer and the revolutionary sample mounting robot, CrystalDirect (http://dx.doi.org/10.1107/s2059798316000954 http://dx.doi.org/10.1107/s0907444912031459) will also be installed on the beamline bringing automation all the way from pure protein to structure models (see http://dx.doi.org/10.1063/1.5084627)

This is an exciting opportunity  to be involved in the commissioning of an MX beamline at the forefront of automation. This will be a highly collaborative position working with the EMBL instrumentation, HTX and synchrotron teams as well as the ESRF towards the design, construction and operation of the upgraded MASSIF-1 beamline with a focus on expanding its capabilities to support automated fragment screening and crystallography pipelines. You will also contribute to the development of new methods exploiting the unique experimental opportunities provided by the integration of the CrystalDirect technology in a beamline environment. You will also participate in research projects involving fragment screening and development of chemical tools on targets of biomedical relevance.

Please feel free to contact me, Josan Marquez (marquez@embl.fr) or Andrew McCarthy (andrewmc@embl.fr) for informal inquiries - you will need to apply here https://www.embl.fr/jobs/searchjobs/index.php?ref=GR00140&newlang=1&loc[]=4 Closing date is the 15th December and interviews will be 27th January 2020.

Best wishes, Matthew.

Matthew Bowler
Synchrotron Crystallography Group
European Molecular Biology Laboratory
71 avenue des Martyrs 
CS 90181 F-38042 Grenoble
Tel: +33 (0)
Fax: +33 (0)


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