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[ccp4bb] Senior Scientist and Research Associate Structural Biology Positions Open at Confo Therapeutics Gent/Brussels, Belgium

Senior Scientist Structural Biology (GPCR; cryo-EM; Xrays; SBDD; Biophysics)

(Senior) Research Associate Structural Biology (GPCR; cryo-EM, protein tool generation, biophysical/biochemical screening)


We are looking for a highly motivated individuals to join our growing structural biology team as a specialist to lead and support our GPCR cryo-EM efforts. Confo has a unique technology which makes use of antibody VHH fragments or ConfoBodies™ to stabilize GPCRs in a particular biologically active conformation of interest as a superior starting point for protein structure determination and innovative H2L/SBDD process. Recently, Confo secured an exclusive license to the Megabody™ technology. Megabodies enable to produce high resolution cryo-EM structures of membrane proteins, overcoming current protein size limitations and potential preferential orientation issues in the study of GPCRs via cryo-EM. Confo is currently located on the Technology Park in Zwijnaarde/Ghent and on the VUB campus in Brussels. More information about Confo’s technology and strategy can be found on www.confotherapeutics.com.


Senior Scientist Structural Biology (Gent/Brussels)



You should have Ph.D. in a field related to structural biology such as cell biology, biochemistry or biophysics. Experience in the membrane protein structural biology -- either or both x-ray crystallography and electron microscopy -- ideally at the postdoctoral level and/or industrial experience. Moderate or extensive EM experience is preferred. You should be an energetic team player with the ability to model enthusiasm and motivate others to excellence. Ambitious in growing to cryo-EM expert in the membrane protein field and a project leader in drug discovery projects.


(Senior) Research Associate Structural Biology (Brussels)



You should have an advanced degree (BSc/MSc) and at least 3 year experience in a related field in a biotech environment. You should be an expert in molecular biology, recombinant protein _expression_ using insect/mammalian systems and purification methods. The ideal candidate would have also extensive experience in biochemical/biophysical characterization/screening and protein engineering. You should be highly collaborative, self-motivated and team-oriented individual.


Our offer is a competitive compensation package with extensive benefits; an entrepreneurial and stimulating working environment in a growing and ambitious biotech company; excellent career development opportunity, with exposure to all aspects of R&D in the company, with external collaborators and partners.


Do you have the right qualifications and are you up to the challenge of joining our team? Then forward a short motivation letter and your CV to veli-pekka.jaakola@confotherapeutics.com




Veli Jaakola



Veli-Pekka Jaakola
Head of Structural Biology
Confo Therapeutics
Technologiepark 94
9052 Zwijnaarde

+32 471 80 01 56



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