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[ccp4bb] PhD position in the structural mechanisms of ubiquitin signalling

The ubiquitin signalling research group headed by Sonja Lorenz at Rudolf Virchow Center for Experimental Biomedicine, Würzburg, Germany

is recruiting a PhD student

The Lorenz lab explores fundamental mechanisms of how posttranslational modifications encode specificity in cellular signaling with a particular focus on the ubiquitin system. Our lab combines cryo-EM and X-ray crystallography with biophysical, biochemical, and cell biological analyses.

We are supported by the EMBO Young Investigator Program, the Emmy Noether Program of the German Research Foundation, the Mildred Scheel Cancer Center, research unit FOR2314 (“Therapeutic windows”), and the graduate training group GRK2243 (“Understanding ubiquitylation”). The successful candidate will have the opportunity to be affiliated with GRK2243 and investigate the structural mechanisms of an exciting class of enzymes essential for infectious disease.

The Rudolf Virchow Center is a highly competitive international research institute with an outstanding infrastructure. The Lorenz lab has in-house access to state-of-the-art instrumentation in cryo-EM (Titan Krios), X-ray crystallography, and an extensive range of modern biophysical and cell biological equipment. We are integrated into a stimulating environment that includes the Helmholtz Institute for RNA-based Infection Research, the Max Planck Research Group in Systems Immunology, the Biocenter, the Institute for Molecular Infection Biology, and the University Hospital in Würzburg.

Würzburg is located in the beautiful, wine-growing area of Franconia, in proximity of Frankfurt (1 hour by train) and Munich (2 hours).

Applicants should have an MSc or equivalent degree in the life sciences or a related discipline and a passion for structural biology and protein biochemistry. Preliminary experience with cryo-EM or X-ray crystallography would be great, but is not strictly required. Good English language skills are necessary; knowledge of German is not necessary.

The position can begin immediately or upon mutual agreement. Salary will be according to the German TVL scale. In case of equivalent qualifications, disabled applicants will be preferentially considered.

Applications and inquiries should be sent to Sonja Lorenz by email and include a letter of motivation stating research interests and expertise, a CV, and the contact information of at least two references. 
Application deadline: 1 November 2019. Review of applications will begin immediately until the position is filled.

twitter @ SLorenzLab

Sonja Lorenz, PhD
Rudolf Virchow Center for Experimental Biomedicine
University of Würzburg, 97080 Würzburg, Germany
E-mail: sonja.lorenz@virchow.uni-wuerzburg.de

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