A 2-year post-doc position is currently available at the Structural Microbiology Unit, located at the Institut Pasteur in Paris.
Our team has been working on the molecular mechanisms underlying the metabolic plasticity of Actinobacteria, with a special emphasis on the signaling pathways involved (for an overview of the topic and our recent work, please see Wagner et al., Sci. Signal., 2019; Bellinzoni et al., Genes Immun., 2019). The postdoctoral fellow will join an active and multidisciplinary environment, working on Corynebacterium glutamicum enzymes and protein complexes involved in central metabolism, and applying an integrative structural biology approach in which cryo-EM plays a key role. The project is part of a French-German initiative funded by the respective national research agencies (ANR and DFG), and will be performed in collaboration with the groups led by Profs. Michael Bott (Forschungszentrum Jülich) and Bernhard Eikmanns (University of Ulm).
The Structural Microbiology Unit is fully equipped for microbiology and protein biochemistry work, and has a well-established network of collaborations. In addition, the institute’s campus provides a vibrant scientific life as well as access to excellent core facilities. A full range of state-of-the-art equipment for structural biology and biophysics is available, including a Titan Krios and two Glacios microscopes currently undergoing installation. The unit has also regular access to synchrotron beamlines for X-ray crystallography and SAXS.
The position is open from October 2019, although the starting date may be arranged. The ideal candidate is an enthusiastic PhD with a good publication record and a solid background in protein biochemistry and biophysics. Good team spirit and presentation skills in English are essential; experience in dealing with large macromolecular complexes, protein-protein interaction studies and/or cryo-EM would be an asset. Interested candidates should provide a full CV with a summary of previous research experience, a brief statement of interest on the position and contacts of a couple of referees to marco (dot) bellinzoni (at) pasteur (dot) fr. Please send applications or informal enquiries no later than June 5.
Unité de Microbiologie Structurale
25, rue du Dr. Roux
75724 Paris Cedex 15
Tel: +33 (0)1 45688608
Fax: +33 (0)1 45688604
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