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[ccp4bb] IBS/Grenoble: postdoc and PhD openings in time-resolved crystallography at XFELs and synchrotrons

We have immediate openings for two postdoctoral researchers and one PhD student at the Institut de Biologie Structurale (www.ibs.fr) in Grenoble, France, to study the structural dynamics of light-sensitive proteins by time-resolved serial crystallography at XFELs and potentially future 4th generation synchrotrons.

Serial femtosecond crystallography (SFX) at X-ray free electron lasers (XFEL) allows studying the structural dynamics of crystalline proteins by means of time-resolved crystallography (TR-SFX). We apply TR-SFX to explore conformational changes after photon absorption by various light-sensitive proteins on a broad time scale ranging from sub-picoseconds to seconds (Nature Chemistry 10, 31 (2018)). These animate structures obtained by static SFX (J Phys Chem Lett 7, 882 (2016); Nature 539, 43 (2016).

At the postdoctoral level, we are looking for highly motivated individuals with a proven record in macromolecular crystallography with a keen interest in data processing and handling and intermediate-state structure refinement.

At the PhD level, we welcome applications from students trained in protein biophysics, and preferably in crystallography.

If you are interested, please contact either Martin Weik (weik@ibs.fr) or Jacques-Philippe Colletier (colletier@ibs.fr).

Martin Weik
Structural Protein Dynamics Research Team
Institut de Biologie Structurale
71 avenue des Martyrs
38044 Grenoble Cedex 9; France	

Phone:    (33) 4 57 42 85 80	
email: 	weik@ibs.fr

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