[ccp4bb] Postdoc position MAX IV, Lund, Sweden for Fragment screening development within the MX-group

Lund University was founded in 1666 and is repeatedly ranked among the world’s top 100 universities. The University has 40 000 students and 7 400 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

MAX IV is a Swedish national large-scale research laboratory hosted by Lund University. It provides scientists from Sweden as well as internationally, with state-of-the-art instrumentation for research in areas such as engineering, physics, structural biology, chemistry and nanotechnology. Fully developed it will receive more than 2 000 scientists annually, conducting ground-breaking experiments in materials and life sciences using the brilliant X-ray light. As a national laboratory, MAX IV is operated in agreement with governmental regulations, and in compliance with major funders such as the Swedish Research Council (VR) and the Wallenberg Foundation. 250 people are currently employed at MAX IV Laboratory, and 16 beamlines are funded. The facility is in a ramp-up phase with 3 beamlines now receiving users and 13 more scheduled to be commissioned and built to receive users within the next few years. The facility is dimensioned for 25-28 beamlines.

Tasks
You are developing, implementing, testing and using the FragMAX screening platform for efficient fragment screening at BioMAX. This includes the implementation of sample handling at the LP3 laboratory, the constant development of relevant processes to carry out the fragment screening at all levels of our support chain and the support of users during screening experiments and standard beamline support. You play a responsible role to develop and utilize our internal fragment library, FragMAXlib.
You are expected to work both independently and in close collaboration with the entire BioMAX team, the FragMAX project group, industrial collaboration partners as well as other international collaborators and future FragMAX user communities.

Qualifications
Essential requirements:

PhD in relevant scientific field for the FRAGMAX project
Demonstrated experiences in protein crystallography or other structural biology methods
Demonstrated experiences in protein crystallisation
Demonstrated experiences in biological laboratory based automated liquid handling
Very good command of English, both written and spoken

Additional requirements:

Experiences in protein-ligand interactions
Experiences in ligand library design
Experiences in synchrotron based structural biology experiments

Uwe Mueller

Group manager Macromolecular Crystallography

BioMAX beam line manager

MAX IV Laboratory
Lund University

Postal address: P.O. Box 118, SE-221 00 Lund, Sweden
Visiting address: Fotongatan 2, 224 84 Lund, Sweden
Mobile: +46(0)730-655268
E-mail: uwe.muller@maxiv.lu.se

Url: www.maxiv.se

VAT No.: SE 2021 0032 1101