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[ccp4bb] Correct link: 3 year PhD fellowship in the Group of Structural Biology and Drug Development (Luecke group) at the Centre for Molecular Medicine Norway (NCMM), University of Oslo (UiO).

A 3 year PhD fellowship is available in the Group of Structural Biology and Drug Development (Luecke group) at the Centre for Molecular Medicine Norway (NCMM), University of Oslo (UiO).

The Group for Structural Biology and Drug Development investigates medically relevant proteins and protein complexes using biophysical, biochemical and structural approaches.  The projects aim at understanding structure-function relationships with an emphasis on drug discovery.  We employ a variety of biochemical and biophysical techniques (x-ray crystallography, single particle cryo electron microscopy, DSF, ITC, SPR, HDX-MS, SAXS, molecular dynamics simulations etc.).  Externally funded projects include inhibitor discovery targeting the Helicobacter pylori pH acclimation system (a pH-gated urea channel and a cytoplasmic urease), and discovery of compounds that reactivate p53 cancer mutants in vitro and in vivo.  Additional projects are available.

The PhD student will also benefit from career development programs offered both at UiO, the Norwegian BioCat initiative as well as the Nordic EMBL network of the Centre for Molecular Medicine, Norway.

Online application required, deadline 31 Mar 2019:






Prof. Hartmut Luecke

Structural Biology and Drug Discovery Group

Norwegian Centre for Molecular Medicine (NCMM), Nordic EMBL Partnership 

and Institute of Clinical Medicine, University of Oslo

Dept. of Medical Biochemistry, Oslo University Hospital

Oslo, Norway


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