DL-CONF-97-001

RECENT ADVANCES IN PHASING

January, 1997

 

Introduction

Acknowledgements

Invited Speakers’ Contributions

Basic Principles of Anomalous Scattering and MAD.

John R. Helliwell, Manchester

1

Design of Synchrotron Beamlines for MAD Protein Crystallography — ESRF BM14.

A. Thompson, EMBL - France

9

Multiwavelength Anomalous Diffraction in Macromolecular Crystallography.

Janet L. Smith, Purdue, USA

25

Phasing MAD data using MIR programs.

V. Biou, IBS/ESRF Grenoble

41

Advances in MIR and MAD phasing: Maximum-Likelihood Refinement in a Graphical Environment, with SHARP.

E. de La Fortelle and G. Bricogne, LMB, Cambridge

55

Multiwavelength Anomalous Dispersion phasing strategies investigated with a brominated oligonucleotide

Mark R. Peterson, Manchester

69

Case study: MAD Phasing of Desulphoredoxin, an Fe Metalloprotein.

Ian D. Glover and Don Nguti, Keele

77

MAD-DM; At Elettra; A Case Study.

H. Powell, Cambridge

89

Scaling of MAD data.

Philip R. Evans, LMB, Cambridge

97

MASC: A Combination of Multiple-Wavelength Anomalous Diffraction & Contrast Variation.

W. Shepard, M. Ramin, R. Kahn and R. Fourme, Orsay and Grenoble, France

103

Direct Phase Determination by Multi-Beam Diffraction.

Edgar Weckert, Kerstin Hölzer and Klaus Schroer, Karlsruhe, Germany

119

Direct methods — overview for macrocrystallographers.

Z. Dauter & P. Main, York

129

Macromolecular Phasing by Shake and Bake.

Charles M. Weeks, Russ Miller, Buffalo, USA

139

Direct Methods Based on Real/Reciprocal Space Iteration.

George M. Sheldrick, Göttingen, Germany

147

Maximum Entropy Methods and the Bayesian Programme.

G. Bricogne, LMB, Cambridge

159

Holographic methods in X-ray Crystallography.

A. Szöke, H. Szöke and J. Somoza, California

179

The World According to wARP: improvement and extension of crystallographic phases.

A. Perrakis, T. Sixma, K. Wilson, V. Lamzin, The Netherlands/York/EMBL Germany

191

Experimental Low Resolution Envelopes From Solution Scattering.

D. Svergun, Germany

199

Low Resolution Crystallographic Images.

A. Urzhumtsev, V. Lunin, A. Podjarny, IGBMC France/Puschino (Russia)

207