Prof. Vinit Mahajan’s group in Department of Ophthalmology, Stanford School of Medicine is seeking applications for a postdoctoral fellow position from ambitious, enthusiastic, and recent Ph.D. holders or graduate students who are expecting to finish his/her graduate degree in structural biology, biophysics, biochemistry, bioengineering, molecular cell biology, or pharmaceutics. The successful candidate will be a structural biologist with strong interests in biomedical, translational, and pharmaceutical sciences, who can carry out one or few structural biology projects for eye disease proteins. Dr. Mahajan is a physician/surgeon, and a scientist, who is the vice chair for research and the director of Molecular Surgery Program of the Stanford’s Byers Eye Institute. He runs a large interdisciplinary group of scientists and clinicians, who are actively seeking for therapeutics and cure for eye patients (https://mahajanlab.stanford.edu/).
Mahajan group is pursuing structural biology research focused on eye diseases in a close collaboration with Prof. Soichi Wakatsuki, Structural Biology Department, Stanford School of Medicine and SLAC National Accelerator Laboratory (http://med.stanford.edu/wakatsukilab.html). Dr. Wakatsuki’s interests cover protein-protein interactions (Comerci & Herrmann et al. Nat. Comm. 2019; Herrmann et al. PNAS 2019), enzyme dynamics (Stoffel et al. PNAS 2019), and structure-based drug design (Hwang et. al., Nat. Comm. 2018).
Both Drs. Mahajan and Wakatsuki are members of Stanford BioX
and ChEM-H, interdisciplinary institutes encompassing three
Stanford Schools: Medicine, Chemistry, and Engineering. This
provides a truly interdisciplinary research environment at the
crossroad of medical science, structural biology and
state-of-the art bioimaging technologies. The two groups
collaborate closely on structural biology research on eye
disease proteins. See one of our recent publications on the
structure-function investigation of a cysteine protease:
Calpain-5 (Velez et al. Cell Reports 2020). Other ophthalmologic
structural biology work includes: 1) targeted
structure-functionomics for eye diseases; and 2) structure-based
drug design for retinal degeneration.
SLAC provides state-of-the-art multi-modal structural biology
technologies covering a wide range of spatiotemporal
resolutions. SLAC hosts large scale infrastructures: SSRL
Structural Molecular Biology (SMB), and Linac Coherent Light
Source (LC/LS) providing synchrotron and X-ray beams for
crystallography, scattering and spectroscopy, and Stanford-SLAC
CryoEM Center (S2C2) providing access to the cryoelectron
microscopy (Cryo-EM) instruments for both single particle
structural analysis and tomography (CryoET).
Qualifications: Ph.D. or equivalent degree in the
relevant fields within the last 3 years. English proficiency is
mandatory. Familiarity with one or more of structural biology
techniques, including X-ray crystallography, small angle X-ray
scattering, cryoEM/ET, biocomputation, and hybrid methods, as
well as strong background and experiences in sample preparation
and characterization. The applicant must be a good team player.
Experiences in scientific writing and grant application to US
funding agencies are plus.
Deadline: as soon as the position is filled.
See the following websites for more information:
With best wishes
Vinit Mahajan and Soichi Wakatsuki
Soichi Wakatsuki, Ph.D.
Professor of Photon Science
SLAC National Accelerator Laboratory
2575 Sand Hill Road, MS 69
Menlo Park, CA 94025-7015
Tel: 1-650-926-4147, Fax:1-650-926-4100
Professor of Structural Biology
School of Medicine
James H. Clark Center W250A
318 Campus Drive
Stanford, CA 94305-5014
To unsubscribe from the CCP4BB list, click the following link: