Postdoctoral position opens at the University of Massachusetts Medical School, in the Korostelev Lab: https://www.umassmed.edu/
We study translation regulation, using cryo-EM and biochemistry. We are particularly interested in:
(1) Translation accuracy; (2) Ribosome's central role in bacterial stress signaling and gene regulation; (3) Neurodegenerative and other diseases, which originate from dysregulation of translation. References to some lab publications are provided below.
Our laboratory is housed at the RNA Therapeutics Institute, a vibrant and highly interactive research community: https://www.umassmed.edu/rti/
(i) previous work - focusing on your most interesting finding(s);
(ii) your current/future scientific interests, and whether/which aspects of translation regulation sound interesting to you;
3) email addresses of three references.
Selected publications (accessible via the provided links):
- Svidritskiy et al. “Extensive ribosome and RF2 rearrangements during translation termination”. eLife. 2019.
- Loveland et al. “Ensemble cryo-EM elucidates the mechanism of translation fidelity”. Nature. 2017.
- Demo et al. “Structure of RNA polymerase bound to ribosomal 30S subunit”. eLife. 2017.
- Abeyrathne et al. “Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome”. eLife. 2016.
- Loveland et al. “Ribosome•RelA structures reveal the mechanism of stringent response activation”. eLife. 2016.
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