We are looking for a PhD candidate (m/f/d) and a Postdoctoral researcher (m/f/d) to strengthen our structural biology/biochemistry team at the Humboldt-Universität zu Berlin (HU).
Our research focuses on the biochemical principles how archaea and bacteria use carbon monoxide (CO) and carbon dioxide (CO2) as carbon and/or energy source. We use protein crystallography in combination with protein chemistry/spectroscopy and kinetics to study the structure, mechanism and assembly of the (multi)complex metalloenzymes at the heart of these molecular energy conversions.
Our laboratory has state-of-the-art facilities for protein production, biochemical characterisation, and protein crystallisation/x-ray crystallography. HU is a member of the Joint Berlin MX-Laboratory, enabling direct access to the local synchrotron facility (BESSY II, Berlin).
For more details see: https://www.biologie.hu-berlin.de/en/gruppenseiten-en/struktbio
You should have a university degree and PhD in biochemistry, chemistry, biophysics or biology. Expertise in either x-ray crystallography, preparative (recombinant) protein production and/or functional characterisation is essential. Previous research experience should be documented through peer-reviewed publications (at least one as first author).
The focus of your contribution to the research projects will be on cofactor-dependent enzymatic reactions, protein crystallography and enzymology. You will contribute to the lectures by assisting in the design, organisation and supervision of lectures, seminars and practical courses. These tasks will allow you to acquire and train skills for further academic qualifications.
You should have a university degree in biochemistry, chemistry, biophysics or biology. Experience in biochemical, biophysical and structural biology methods, especially in the characterisation of enzymes is welcome.
You will work in the research project “Fe/S-double-cubane-cluster: a new cofactor in biology (DCCP)” within the priority program “Fe/S-clusters for life” (https://www.ironsulfurforlife.de). Your tasks are the purification and the biochemical and structural characterization of oxygen-sensitive metalloenzymes in order to elucidate the role of Fe/S-double cubane-clusters.
Both positions are funded for 3 years (German salary level E 13 TV-L HU for postdoctoral fellow, 0,65 E 13 TV-L for PhD fellow). Please submit your application (letter of application, CV and two references) preferentially electronically (a single PDF file not exceeding 10 MB) with a subject line “AN/300/19” for the postdoctoral position and “DR/187/19” for the PhD position. Deadline for application is 30.10.2019.
Email contact: firstname.lastname@example.org
Humboldt-Universität zu Berlin
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