Preface

Invited Speakers’ Contributions

Theory of errors

J.S. Rollet, University of Oxford

Errors in macromolecular crystallographic data collection with area detector instruments

P.A. Tucker, EMBL, Heidelberg

Notes on the errors of phase determination in the multiple isomorphous replacement method and the molecular replacement method

Z. Derewenda, University of York

Analysis of errors found in protein structure co-ordinates in the Brookhaven Data Bank

J.M. Thornton, M.W. McArthur, D.K. Smith, S.P. Gardner, E.G. Hutchinson, A.L. Morris and B.L. Sibanda, Birkbeck College, London

Bad contacts in protein structures

S.A. Islam and M.J.E. Sternberg, Imperial Cancer Research Fund, London, and D.L. Weaver, TUFTS University

Structure determination of turkey egg lysozyme

S.E.V. Phillips, W.S. Somers, T.N. Bhat and M.R. Parsons, University of Leeds

The RuBisCO saga

H.A. Schreuder, P.M.G. Curmi, D. Cascio and D. Eisenberg, University College of Los Angeles

Validation of protein structures — a case study: the small subunit of Rubisco

S. Knight, I. Anderson and C-I. Brändén, Swedish University of Agricultural Sciences, Uppsala

Hallmarks of a wrong structure

C.D. Stout, Research Institute of Scripps Clinic

A tale of four iron-sulfur proteins: sequence errors and other matters

E.T. Adman, University of Washington

Discussion Contribution

Uncertainty and bias in difference Fourier maps

U. Derewenda, E. Dodson, G. Dodson, D. Hodgkin, and H. Swift, University of York

Summary

Accuracy and reliability of macromolecular crystal structures

Closing remarks

D. Blow, Imperial College, London