Collaborative Computational Project No. 4
Software for Macromolecular X-Ray Crystallography


CCP4 exists to produce and support a world-leading, integrated suite of programs that allows researchers to determine macromolecular structures by X-ray crystallography, and other biophysical techniques. CCP4 aims to develop and support the development of cutting edge approaches to experimental determination and analysis of protein structure, and integrate these approaches into the suite. CCP4 is a community based resource that supports the widest possible researcher community, embracing academic, not for profit, and for profit research. CCP4 aims to play a key role in the education and training of scientists in experimental structural biology. It encourages the wide dissemination of new ideas, techniques and practice.

PDB Deposition Rules Changed
New! PDB Deposition switches to mmCIF format on the 1st of July 2019. Deposition files in mmCIF format can be generated using CCP4i2 or CCP4Cloud
CCP4 Twitter Feed
CCP4 Twitter CCP4 twitter feed for all the latest updates and community announcements
CCP4 Software Suite
The current version is CCP4 7.1 (23 April 2020). Details available here.
The new packages include:
  • CCP4I2: new ccp4 interface
  • DIALS: data processing and integration
  • CCP4Cloud Client: CCP4Cloud Client
  • SHELX suite: co distribution for academic users
The updated packages include PHASER, XIA2, REFMAC, MONOMER LIBRARY, AMPLE, COOT, AIMLESS POINTLESS, CTRUNCATE, DIMPLE, BLEND and many more
Virtual CCP4 Study Weekend 2021
  • Integrating Structural Biology with scientific organisers Dr Atlanta Cook (University of Edinburgh), Prof Dan Rigden (University of Liverpool) and Prof Tassos Perrakis (Netherlands Cancer Institute, The Netherlands). 5-8 Jan. 2021`
    [Information] [Agenda] [Registration]
CCP4 Study Weekend 2020
CCP4 special issue Proceedings of the 2017 Study Weekend on From Crystal to Structure... are now available. For more information about past events see details of past Study Weekends and proceedings.
CCP4 Online Automated Webservices
ccp4online The CCP4-online webserver is now available. Users can make use of BALBES, MrBUMP and MoRDa, the automated molecular replacement services. Zanuda, the refinement result checking software and PISA for the calculation and analysis of macromolecular surfaces and interfaces are also available, as well as CRANK2 and SHELX pipelines for experimental phasing. To access the services please click here.
CCP4 Documentation Wiki
CCP4 Wiki For up-to-date documentation on all of CCP4's software and lots of other useful information for X-ray crystallographers see the CCP4 Wiki.
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